Browse by Department

Mina, J.G. and Mosely, J.A. and Ali, H.Z. and Shams-Eldin, H. and Schwarz, R.T. and Steel, P.G. and Denny, P.W. (2010) 'A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase.', International journal of biochemistry and cell biology., 42 (9). pp. 1553-1561.

Cobb, S.L. and Denny, P.W. (2010) 'Antimicrobial peptides for leishmaniasis.', Current opinion in investigational drugs., 11 (8). pp. 868-875.

Mina, J. G. and Okada, Y. and Wansadhipathi, N. K. and Pratt, S. and Shams-Eldin, H. and Schwarz, R. T. and Steel, P. G. and Fawcett, T. and Denny, P. W. (2010) 'Functional analyses of differentially expressed isoforms of the Arabidopsis inositol phosphorylceramide synthase.', Plant molecular biology., 73 (4-5). pp. 399-407.

Mina, J. G. and Pan, S. Y. and Wansadhipathi, N. K. and Bruce, C. and Shams-Eldin, H. and Schwarz, R. T. and Steel, P. G. and Denny, P. W. (2009) 'The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.', Molecular and biochemical parasitology., 168 (1). pp. 16-23.

Tran, T. L. and Castagné, N. and Dubosclard, V. and Noinville, S. and Koch, E. and Moudjou, M. and Henry, C. and Bernard, J. and Yeo, R. P. and Eléouët, J. F. (2009) 'The respiratory syncytial virus M2-1 protein forms tetramers and interacts with RNA and P in a competitive manner.', Journal of virology., 83 (13). pp. 6363-6374.

Money, V. A. and McPhee, H. K. and Mosely, J. A. and Sanderson, J. M. and Yeo, R. P. (2009) 'Surface features of a mononegavirales matrix protein indicate sites of membrane interaction.', Proceedings of the National Academy of Sciences of the United States of America., 106 (11). pp. 4441-4446.

MacLellan, K. and Loney, C and Yeo, R. P. and Bhella, D. (2007) 'The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings.', Journal of virology., 81 (17). pp. 9519-9524.

Lin, Y-F. and Walmsley, A. R. and Rosen, B. P. (2006) 'An arsenic metallochaperone for an arsenic detoxification pump.', Proceedings of the National Academy of Sciences of the United States of America., 103 (42). pp. 15617-15622.

Cope, H. and Mutter, R. and Heal, W. and Pascoe, C. and Brown, P. and Pratt, S. and Chen, B. (2006) 'Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.', European journal of medicinal chemistry., 41 (10). pp. 1124-1143.

Denny, P. W. and Shams-Eldin, H. and Price, H. P. and Smith, D. F. and Schwarz, R. T. (2006) 'The protozoan inositol phosphorylceramide synthase : a novel drug target that defines a new class of sphingolipid synthase.', Journal of biological chemistry., 281 (38). pp. 28200-28209.

Gottschalg, E. and Moore, N. E. and Ryan, A. K. and Travis, L. C. and Waller, R. C. and Pratt, S. and Atmaca, M. and Kind, C. N. and Fry, J. R. (2006) 'Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression : implications for fingerprint profiling of cytotoxicity.', Chemico-biological interactions., 161 (3). pp. 251-261.

Touil, F. and Pratt, S. and Mutter, R. and Chen, B. (2006) 'Screening a library of potential prion therapeutics against cellular prion proteins and insights into their mode of biological activities by surface plasmon resonance.', Journal of pharmaceutical and biomedical analysis., 40 (3). pp. 822-832.

Reddy, T. R. K. and Mutter, R. and Heal, W. and Guo, K. and Pratt, S. and Gillet, V. and Chen, B. (2006) 'Library design, synthesis and screening : pyridine dicarbonitriles as potential prion disease therapeutics.', Journal of medicinal chemistry., 49 (2). pp. 607-615.

Maxwell, K. L. and Reed, P. and Zhang, R. G. and Beasley, S. and Walmsley, A. R. and Curtis, F. A. and Joachimiak, A. and Edwards, A. M. and Sharples, G. J. (2005) 'Functional similarities between phage lambda Orf and Escherichia coli RecFOR in initiation of genetic exchange.', Proceedings of the National Academy of Sciences of the United States of America., 102 (32). pp. 11260-11265.

Morgan, G. W. and Denny, P. W. and Vaughan, S. and Goulding, D. and Jeffries, T. R. and Smith, D. F. and Gull, K. and Field, M. C. (2005) 'An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in trypanosoma brucei.', Molecular and cellular biology., 25 (9). pp. 3774-3783.

Federici, L. and Du, D. and Walas, F. and Matsumura, H. and Fernandez-Recio, J. and McKeegan, K. S. and Borges-Walmsley, M. I. and Luisi, B. F. and Walmsley, A. R. (2005) 'The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 Å resolution.', Journal of biological chemistry., 280 (15). pp. 15307-15314.

Farzaneh, P. and Allameh, A. and Pratt, S. and Moore, N. and Travis, L. and Gottschalg, E. and Kind, C. and Fry, J. (2005) 'Increased heat shock protein 70 expression following toxicant-mediated cytotoxicity : a ubiquitous marker of toxicant exposure ?', ATLA, 33 (2). pp. 105-110.

Curtis, F. A. and Reed, P. and Sharples, G. J (2005) 'Evolution of a phage RuvC endonuclease for resolution of both Holliday and branched DNA junctions.', Molecular microbiology., 55 (5). pp. 1332-1345.

Stegmayer, C. and Kehlenbach, A. and Tournaviti, S. and Wegehingel, S. and Zehe, C. and Denny, P. and Smith, D. F. and Schwappach, B. and Nickel, W. (2005) 'Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant.', Journal of cell science., 118 (3). pp. 517-527.

Denny, P. W. and Morgan, G. W. and Field, M. C. and Smith, D. F. (2005) 'Leishmania major : clathrin and adaptin complexes of an intra-cellular parasite.', Experimental parasitology., 109 (1). pp. 33-37.

Denny, P. W. and Smith, D. F. (2004) 'Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa.', Molecular microbiology., 53 (3). pp. 725-733.

Bhella, D. and Ralph, A. and Yeo, R. P. (2004) 'Conformational flexibility in recombinant measles virus nucleocapsids visualised by cryo-negative stain electron microscopy and real-space helical reconstruction.', Journal of molecular biology., 340 (2). pp. 319-331.

Sharples, G. J. and Curtis, F. A. and McGlynn, P. and Bolt, E. L. (2004) 'Holliday junction binding and resolution by the rap structure-specific endonuclease of phage lambda.', Journal of molecular biology., 340 (4). pp. 739-751.

Pratt, S. and Gottschalg, E. and Atmaca, M. and Kind, C. N. and Fry, J. R. (2004) 'Heat shock protein induction by sodium arsenite and cadmium chloride in rat hepatocytes and rat FGC4 hepatoma cells.', Toxicology., 194 (3). pp. 235-236.

Denny, P. W. and Goulding, D. and Ferguson, M. A. J. and Smith, D. F. (2004) 'Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity.', Molecular microbiology., 52 (2). pp. 313-327.

Zufferey, R. and Allen, S. and Barron, T. and Sullivan, D. R. and Denny, P. W. and Almeida, I.C. and Smith, D. F. and Turco, S. J. and Ferguson, M. A. J. and Beverley, S. M. (2003) 'Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.', Journal of biological chemistry., 278 (45). pp. 44708-44718.

Borges-Walmsley, M. I. and Beauchamp, J. and Kelly, S. M. and Jumel, K. and Candlish, D. and Harding, S. E. and Price, N. C. and Walmsley, A. (2003) 'Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA.', Journal of biological chemistry., 278 (15). pp. 12903-12912.

Murphy, L. B. and Loney, C. and Murray, J. and Bhella, D. and Ashton, P. and Yeo, R. (2003) 'Investigations into the amino-terminal domain of the respiratory syncytial virus nucleocapsid protein reveal elements important for nucleocapsid formation and interaction with the phosphoprotein.', Virology., 307 (1). pp. 143-153.

Morgan, G. W. and Hall, B. S. and Denny, P. W. and Field, M. C. and Carrington, M. (2002) 'The endocytic apparatus of the kinetoplastida : Part II : machinery and components of the system.', Trends in parasitology., 18 (12). pp. 540-546.

Morgan, G. W. and Hall, B. S. and Denny, P. W. and Carrington, M. and Field, M. C. (2002) 'The kinetoplastida endocytic apparatus. Part I : a dynamic system for nutrition and evasion of host defences.', Trends in parasitology., 18 (11). pp. 491-496.

Henderson, G. and Murray, J. and Yeo, R. P. (2002) 'Sorting of the respiratory syncytial virus matrix protein into detergent-resistant structures is dependent on cell-surface expression of the glycoproteins.', Virology., 300 (2). pp. 244-254.

Denny, P. W. and Lewis, S. and Tempero, J. E. and Goulding, D. and Ivens, A. C. and Field, M. C. and Smith, D. F. (2002) 'Leishmania RAB7 : characterisation of terminal endocytic stages in an intracellular parasite.', Molecular and biochemical parasitology., 123 (2). pp. 105-113.

Song, L. and Rosen, B. P. and Borges-Walmsley, M. I. and Walmsley, A. (2002) 'Evidence for cooperativity between the four binding sites of dimeric ArsD, an As (III)-responsive transcriptional regulator.', Journal of biological chemistry., 277 (29). pp. 25992-26002.

Sharples, G. J. and Bolt, E. L. and Lloyd, R. G. (2002) 'RusA proteins from the extreme thermophile Aquifex aeolicus and lactococcal phage r1t resolve Holliday junctions.', Molecular microbiology., 44 (2). pp. 549-559.

Murray, J. and Loney, C. and Murphy, L. B. and Graham, S. and Yeo, R. P. (2001) 'Characterization of monoclonal antibodies raised against recombinant respiratory syncytial virus nucleocapsid (N) protein : identification of a region in the carboxy terminus of N involved in the interaction with P protein.', Virology., 289 (2). pp. 252-261.

McKean, P. G. and Denny, P. W. and Knuepfer, E. and Keen, J. K. and Smith, D. F. (2001) 'Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania.', Cellular microbiology., 3 (8). pp. 511-523.

Denny, P. W. and Smith, D. F. (2001) 'Meeting report : molecular Parasitology XI, Woods Hole, USA, September 17-21, 2000.', Protist., 152 (1). pp. 3-6.

Walmsley, A. and Zhou, T. and Borges-Walmsley, M. I. and Rosen, B. P. (2001) 'A kinetic model for the action of a resistance efflux pump.', Journal of biological chemistry., 276 (9). pp. 6378-6391.

Denny, P.W. and Field, M.C. and Smith, D.F. (2001) 'GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida.', FEBS letters., 491 (1-2). pp. 148-153.

Williamson, D. H. and Denny, P. W. and Moore, P. W. and Sato, S. and McCready, S. and Wilson, R. J. M. (2001) 'The in vivo conformation of the plastid DNA of toxoplasma gondii : implications for replication.', Journal of molecular biology., 306 (2). pp. 159-168.

List was generated at Thu Nov 28 12:33:09 2024 GMT.